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Scientists Turn Cancer Drug Resistance into an Immunotherapy Advantage

Rethinking Cancer Drug Resistance

Cancer treatment often faces a critical setback when tumours stop responding to medicines that initially work well. In advanced and metastatic cancers, tumour cells frequently acquire new genetic mutations that allow them to bypass targeted drugs. This acquired resistance remains one of the biggest barriers to durable cancer control, even with cutting-edge therapies.

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Guinea Returns to Civilian Rule as Coup Leader Mamady Doumbouya Elected President

Election Outcome and Provisional Results

Guinea’s long-awaited transition to civilian governance has been formalised with Mamady Doumbouya winning the presidential election, according to provisional results announced on December 31, 2025. The head of the electoral authority said Doumbouya secured 86.72 per cent of the vote in the December 28 polls, avoiding a second round. Voter turnout was officially pegged at 80.95 per cent, though opposition groups questioned participation levels, particularly in the capital Conakry. Guinea’s Supreme Court has up to eight days to confirm the outcome if petitions are filed. The result grants Doumbouya a seven-year presidential term.

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Delhi Cabinet Clears Jan Vishwas Bill 2026 to Decriminalise Minor Offences

Cabinet Approval for Key Governance Reform

The Delhi Cabinet has approved the Delhi Jan Vishwas (Amendment of Provisions) Bill, 2026, marking a major step towards simplifying regulatory compliance and reducing unnecessary criminalisation in the National Capital. The reform is aimed at improving both ease of doing business and ease of living by replacing criminal penalties for minor violations with proportionate civil measures.

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Pariksha Pe Charcha 2026 Crosses 3 Crore Registrations, Sets New Record

Record-Breaking Participation Milestone

Pariksha Pe Charcha (PPC), the flagship student outreach programme of Prime Minister Narendra Modi, has achieved its highest-ever participation, with registrations crossing 3 crore as of December 30, 2025. The Ministry of Education termed this the largest engagement since the initiative’s inception, highlighting its expanding reach across India’s education ecosystem.

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Ahmedabad’s IKDRC Sets National Record With 500 Kidney Transplants in 2025

Record-Breaking Achievement in Public Healthcare

The Institute of Kidney Diseases and Research Centre (IKDRC) at Ahmedabad Civil Medical College has created a new benchmark in India’s public healthcare system by completing 500 kidney transplants in a single calendar year. Achieved in 2025, this feat makes IKDRC the only government-run hospital in the country to reach such a volume within one year, highlighting its leadership in affordable and advanced transplant care.

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